< Back to Blog Listings

Significant New Use of Certain Chemical Substances

chemical in barrels-blog

The EPA is issuing significant new use rules (SNURs) under the Toxic Substances Control Act (TSCA) for chemical substances that are the subject of pre-manufacture notices (PMNs). This action requires persons to notify EPA at least 90 days before commencing manufacture (defined by statute to include import) or processing of any of these chemical substances for an activity that is designated as a significant new use by this rule. The required notification initiates EPA’s evaluation of the chemical under the conditions of use within the applicable review period.

Persons may not commence manufacture or processing for the significant new use until EPA has conducted a review of the Significant New Use Notice (SNUN), made an appropriate determination on the SNUN, and has taken such actions as are required as a result of that determination.


  • 1H-imidazole-1-propanenitrile,2-ethylar-methyl- (CAS No. 568591–00–4)
  • 2,4-hexadien-1-ol, 1-acetate, (2E,4E)- (PMN P–17–324, (CAS No. 57006–69–6)
  • 2-Alkenoic acid, 2-alkyl-, alkyl ester, polymer with 2-(dialkylamino)alkyl 2- alkyl-2-alkenoate, alkyl 2-alkyl-2-alkenoate and a-(2-alkyl-1-oxo-2-alken-1-yl)-oalkoxypoly(oxy-1,2-alkanediyl), [(1-alkoxy-2- alkyl-1-alken-1-yl)oxy]trialkylsilane-initiated (generic).
  • Benzenesulfonamide, N-[2- [[(phenylamino)carbonyl] amino]phenyl]- (CAS No. 215917–77–4)
  • Lithium, isotope of mass 6 (CAS No. 14258–72–1)
  • Silsesquioxanes, 3- (dimethyloctadecylammonio)propyl Me Pr, polymers with silicic acid (H4SiO4) tetra-Et ester, (2-hydroxyethoxy)- and methoxy-terminated, chlorides (CAS No. 35501–23–6)

More information on this and other regulations are available on AIAG’s Regulatory Updates C2P page, which automatically pulls in new and relevant content as it becomes available. The content is brought to you via Compliance & Risks and their knowledge partner network. 

The RSS feed-driven page is geared toward individuals involved with corporate responsibility and sustainability (CR/S), those performing quality functions that require reporting into IMDS, and all others dealing with global substances of concern and waste regulation. The page’s simple and straightforward format allows users to quickly skim through content if desired, but also makes it easy to find more information. Clicking on any particular update’s title takes the user to the source page, where more detail is available. Since the page populates with fresh content as regulations are updated and customer requirements change, the process of staying informed is made stress-free.

Checking back often will help individuals stay up to date on the latest need-to-know regulations and requirements and stay better prepared for compliance challenges. Additionally, although new content appearing at the top of the page will displace older updates, the latter will still be readily available simply by scrolling down.

For more information, contact Lecedra Welch, AIAG’s program manager for environmental sustainability, at CR@aiag.org.